I am not sure when or for what reason, but the shedding of my hair from the Methotrexate seems to have slowed down. When I first started back on Methotrexate I had a lot of hair shedding as I did the entire time I was on it in the past. Every time I ran my fingers through my hair, brushed my hair out, or took a shower large amounts of hair would come out. I have noticed for some weeks now that the amount of hair coming out is pretty much normal again. I don’t know what made this change, but I am not complaining!